|
ATENOLOL |
| Product Name |
: |
Atenolol BP/EP/USP |
| Chemical Name |
: |
Benzenacetamide, 4-[2-hydroxy-3-[(1-methylethyl)amino]propoxy] -2[p-[2-Hydroxy-3-(isopropylamino)propoxy]-phenyl]acetamide |
| CAS Number |
: |
29122-68-7 |
| Chemical Formula |
: |
C14H22N2O3 |
| Molecular Mass |
: |
266.34 g/mol |
| Therapeutic Category |
: |
Antagonist |
| Test |
Specification |
| Description |
White or almost white powder |
| Identification |
By UV Absorbance ratio 1.15 to 1.20 at 275 to 282nm By TLC : To comply Melting range : 152° TO 155°C |
| Solubility |
Sparingly soluble in water, soluble in ethanol, Slightly soluble in methylene chloride practically insoluble in ether. |
| Appearance of Solution |
The solution should clear and not more intensely colored than degree 6 of the range of reference solution of the most appropriate colour. |
| Loss On Drying |
Not More Than : 0.50 % |
| Assay on dried basis by HPLC |
99.0 % to 101 % |
| Optical Rotation |
+ 0.10 to 0.10 |
| Sulphated Ash |
Not More Than : 0.1 % |
| Related Substances by HPLC |
Single impurity: Not More Than : 0.25 % Total impurity: Not More Than : 0.50 % |
| Chloride |
Not More Than : 0.1 % |
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