|
HALOPERIDOL |
| Product Name |
: |
Haloperidol BP/EP/USP |
| Chemical Name |
: |
4-[4-(4-chlorophenyl)-4-hydroxy-1-piperidyl]-1-(4-fluorophenyl)-butan-1-one |
| CAS Number |
: |
52-86-8 |
| Chemical Formula |
: |
C21H23ClFNO2 |
| Molecular Mass |
: |
375.9 g/mol |
| Therapeutic Category |
: |
antipsychotic |
| Test |
Specification |
| Description |
A white or almost white powder. |
| Identification |
The IR spectrum of sample should match with that of standard. A curdy, white precipitate is produced |
| Solubility |
Practically insoluble in water, soluble in alcohol, in methanol & in methylene chloride. |
| Appearance of Solution |
The solution is clear and not more intensely coloured than reference solution Y7 |
| Heavy Metals |
NMT 20 ppm |
| Loss On Drying |
NMT 0.5% |
| Assay on dried basis by HPLC |
NLT 99% and NMT 101% |
| Sulphated Ash |
NMT 0.1% |
| Related Substances by HPLC |
Individual impurity : NMT 0.5% Total impurities : NMT 1.0% |
| Related Substances by TLC |
Position & size of principal spot obtained with sample shall be similar with that of standard. |
| Chloride |
A curdy, white precipitate is produced. |
| Melting Range |
Between 150°C & 153°C |
| Clarity & Colour Solution |
A violet colour is produced and becomes brownish red after 20 min |
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